Drug Uses
Use Estrandiol to reduce moderate to severe menopausal symptoms, to treat vulval and vaginal atrophy, treat certain cancers in special situations and prevent the thinning of bones.
How Taken
Talk to your local physician or pharmacist. You and your doctor should reevaluate whether or not you still need estrogens at least every six months.
Warnings/Precautions
If you think you may be pregnant, do not use any form of estrogen-containing drug. Using Estrandiol while you are pregnant may cause your unborn child to have birth defects. Estrandiol does not prevent miscarriage.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Possible Side Effects
The following side effects have been reported with use of this medicine: nausea and vomiting; breast tenderness or enlargement; enlargement of benign tumors; retention of excess fluid (this may make some conditions worsen, such as asthma, epilepsy, migraine, heart disease, or kidney disease); a spotty darken of the skin, particularly on the face.
Storage
Store at controlled room temperature 15°C to 30°C (59°F to 86°F). Keep this and all drugs out of the reach of children.
Overdose
In case of overdose, call your doctor, hospital or poison control center immediately.
More Information
You are cautioned to discuss very carefully with your doctor or health care provider all the possible risks and benefits of long-term estrogen and progestin treatment as they affect you personally.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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FRIDAY, Sept. 14 (HealthDay News) -- The Eli Lilly drug Evista (raloxifene) has been approved by the U.S. Food and Drug Administration to reduce the risk of invasive breast cancer among postmenopausal at high risk for the disease and among postmenopausal women with osteoporosis.
Latest Cancer News
The agency's decision followed recommended approval in July for these new uses by an FDA expert advisory panel, despite concerns that the drug could increase the risks of blood clots and fatal stroke in some women.
Evista was first approved in 1999 to prevent osteoporosis in postmenopausal women.
In a statement, Lilly said the drug's label would now include a boxed warning stressing that women with a history of blood clots known as venous thromboembolisms should not take Evista, and that women at risk for stroke should consult a physician before using the drug.
Women who are pregnant, nursing or who could become pregnant shouldn't take the drug either, Lilly said, and those with kidney or liver problems should speak with their doctor first.
THURSDAY, Oct. 11 (HealthDay News) -- Obese people are six times more likely to develop esophageal cancer than people with healthy weight, says an Australian study that looked at 800 people with esophageal tumors and 1,600 people without the disease.
Latest Cancer News
People with a body mass index (BMI) of 40 or more were six times as likely to have esophageal cancer as those with a BMI between 18.5 and 25 (a BMI of 30 is considered the threshold for obesity).
According to a team from the Queensland Institute of Medical Research in Brisbane, the finding held true even after accounting for other factors known to be linked to the disease, such as high alcohol consumption and smoking.
This suggests that obesity is an independent risk factor for esophageal cancer, said the study authors, who explained that higher levels of fat tissue in the body increase insulin production. This, in turn, boosts levels of circulating insulin-like growth factor.
Both these hormones stimulate cell growth and inhibit cell death -- conditions that can lead to cancer development, the team said.
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